The product consist of essential components required for the proper functioning of the body. It is mainly employed in old age people suffering from Osteoarthritis which is one of the most prevalent and disabling chronic diseases nowadays. Daily intake of sachet will help rebuild cartilage, help improve flexibility and mobility in people affected with OA. Those who have high risk of developing OA may also consume this sachet regularly for prevention.

Uses:

⇒ Maintains connective tissue
⇒ Improves immune function
⇒ Reduce bone resorption
⇒ Helps to improve the integrity and flexibility of bones
⇒ Effective in osteoarthritis
⇒ Anti-inflammatory
⇒ Antioxidant

About Composition:

Glucosamine is a naturally occurring substance and is an amino sugar and precursor of glycosylated proteins and lipids. It is believed to help develop and renew cartilage (the hard connective tissue mainly located on bones near joints in the body), and keep it lubricated for better joint movement and flexibility.

Rose hips suggested uses include as a rich source of Vitamin C, remedy for rheumatoid arthritis; reduces symptoms of knee and hip osteoarthritis; helps the immune system to fight off foreign invaders and out of control cells; facilitates fat metabolism; protects tissues from free radical damage; assists the nervous system by converting certain amino acids into neurotransmitters; prevents scurvy; protects joints and connective tissues; protects adrenal function; ability to prevent urinary bladder infections, and assist in treating dizziness and headaches; used externally in oil form to restore firmness to skin by nourishing and astringing tissue; brewed into a decoction, can also be used to treat constipation; and rose hips contain lots of iron, rose hip tea is used during menstruation to make up for iron loss.

Chondroitin sulfate is a glycosaminoglycan considered as a symptomatic slow-acting drug for osteoarthritis. Chondroitin sulfate functions as a major component of the intricate extracellular matrix. It is proposed that chondroitin sulfate supply can provide new building blocks for the synthesis of new matrix components. The anti-inflammatory effect of chondroitin sulfate is thought to be caused by the inhibition of the synthesis of inflammatory intermediates such as the inhibition of nitric oxide synthase, COX-2, microsomal prostaglandin synthase 1 and prostaglandin E2. It is reported also an inhibitory activity in the toll-like receptor 4 which will later inhibit inflammatory cytokines, NFkB and MyD88. This activity suggests a modulation of the MAP kinase pathway. On the other hand, some reports have pointed out an induction on the PKC/PI3K/Akt pathway in neuroblastoma.

Collagen is the main structural protein in the extracellular matrix in the various connective tissues in the body. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole-body protein content. Collagen consists of amino acids bound together to form a triple helix of elongated fibril known as a collagen helix. It is mostly found in fibrous tissues such as tendons, ligaments, and skin. Over 90% of the collagen in the human body is type I collagen. However, 30 types of collagen have been identified, described, and divided into several groups according to the structure they form: All of the types contain at least one triple helix. The number of types shows collagen's diverse functionality.

Collagens are widely employed in the construction of the artificial skin substitutes used in the management of severe burns and wounds. These collagens may be derived from bovine, equine, porcine, or even human sources; and are sometimes used in combination with silicones, glycosaminoglycans, fibroblasts, growth factors and other substances. When hydrolyzed, collagen is reduced to small peptides, which can be ingested in the form of a dietary supplement or functional foods and beverages with the intent to aid joint and bone health and enhance skin health. Hydrolyzed collagen has a much smaller molecular weight in comparison to native collagen or gelatin. Studies suggest that more than 90% of hydrolyzed collagen is digested and available as small peptides in the blood stream within one hour. From the blood, the peptides (containing hydroxyproline) are transported into the target tissues (e.g., skin, bones, and cartilage), where the peptides act as building blocks for local cells and help boost the production of new collagen fibers.

Vitamin C is needed by the body to form collagen. The body also uses vitamin C to make skin, tendons, ligaments and blood vessels. It also uses this vitamin to repair and maintain cartilage, bones and teeth, to heal wounds and to form scar tissue.

Hyaluronic acid is similar to a substance that occurs naturally in the joints. It may work by acting as a lubricant and shock absorber in the joint, helping the knee to move smoothly, thereby lessening pain. Hyaluronic acid performs its activities as a tissue lubricant and hence, it is thought to be key in the modulation of interactions between adjacent tissues. Hyaluronic acid is a polysaccharide which is distributed widely in the extracellular matrix of connective tissue in man. It forms a viscoelastic solution in water which makes it suitable for aqueous and vitreous humor in ophthalmic surgery. It is suggested to provide mechanical protection for ocular tissues and cell layers due to its high viscosity. The elasticity of the solutions of hyaluronic acid can assist in the absorption of mechanical stress and the generation of a protective buffer for the tissues. This viscoelasticity enables maintenance of a deep chamber during surgical manipulation since the solution does not flow out of the open anterior chamber.

In the area of wound healing, hyaluronic acid acts as a protective vehicle that allows the transport of peptide growth factors and other structural proteins to the site of action. After promoting the transport of key molecules, it is enzymatically degraded and the transported proteins are released to promote tissue repair.

Side Effects:

The product is possible safe for most adults. There is no disadvantage associated with the product if taken under the recommended usage however diarrhoea and rashes can be seen in some patients.

Warning & Precaution:

⇒ Dose should be adjusted in hepatic impairment.
⇒ Diabetes
⇒ Increased risk of bleeding
⇒ Gallstones
⇒ Urinary tract infection

Storage:

⇒ Store in cool and dry place
⇒ Protect from Light
⇒ Keep out of reach of children